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Face and body effects of lipolytic injection and symptoms of inflammation and swelling that diffe...



Woman who cares about fat on upper arm

Fat-dissolving injection is one of the medical diet treatment methods (slimming treatment performed at medical institutions), which is said to destroy and dissolve adipocytes by simply injecting the drug directly into the subcutaneous fat of the face or body .

It acts on extra fat such as under the jaw and upper arm, which is said to be difficult to lose weight with a normal diet such as dietary restrictions, and has the effect of adjusting the line without using a scalpel, while "I do not understand the change" "Internal bleeding There are a lot of reports saying "it has happened".

In order not to regret the fat-soluble injection, it is important to understand the effects and risks/side effects of the fat-soluble injection, such as small face treatment and partial thinning .

Lipolysis injection to reduce fat cells by drug injection

Surprised woman

Unlike liposuction, lipolysis injection does not use anesthesia or a scalpel/suction tube. For this reason, it is said that downtime after treatment is short, such as swelling and swelling, partial thinning of the upper arms, etc., acting not only on the cheeks and under the chin but also on the fat on the nose (dango nose), leading to a clean face line. I am.

Fat-soluble injection is also called Mesotherapy, but originally Mesotherapy means "a method of directly injecting a drug subcutaneously". However, because some clinics use mesotherapy as the treatment name, mesotherapy and lipolytic injection are often treated as synonyms.

Since lipolytic injection is performed with an extremely fine needle, it is a relatively painless treatment method, and it is said to have less damage to blood vessels and nerves like liposuction.

Mechanism of fat loss by lipolysis injection

A lipolytic injection is a slimming treatment that helps reduce subcutaneous fat. When a drug is injected into an area of concern, the fat cells in that area are destroyed, and macrophages (cleaning cells in the body that prey on dead cells) are excreted out of the body along with urine and feces .

Destroyed fat cells do not regenerate

Once destroyed, the fat cells will never regenerate.

The symptoms of obesity are caused by the swelling of fat cells, not the increase in fat cells. It is said that the number of adipocytes does not increase or decrease in adults. Therefore, it can be said that reducing fat cells by lipolytic injection also reduces anxious subcutaneous fat .

Benefits of slimming with fat-soluble injections

Hip fat

Less worry about rebound

It is said that the fat cells at the site where the drug was injected by lipolysis injection are excreted outside the body and the number decreases, and the excreted fat cells do not regenerate . However, due to irregular lifestyles such as overdose, overeating, and lack of exercise , fat cells that have not been destroyed and become large may rebound . It is important to keep a healthy diet and exercise appropriately after the fat-soluble injection.

Aim for partial thinning

It is said that partial weight loss is difficult with a personal diet. It is not easy to keep only the fat you want to keep, such as your chest and hips, even if you are on a diet by exercising, because basal metabolic power decreases and you become hard to lose weight if you restrict your diet.

The fat-soluble injection is said to act only on the fat at the drug injection site, so it may be possible to aim for partial weight loss without difficulty .

Smooth cellulite

The irregularities on the skin that appear on the thighs and hip lines are generally called cellulite, but they are said to have the same structure as other subcutaneous fat. Therefore, it can be said that by injecting a drug into the area where cellulite is a concern with a lipolytic injection to destroy and remove fat cells, the unevenness of the skin can be smoothed .

Lead to small face improvement

One of the reasons why the fat on the face is hard to remove is related to the function of the facial muscles.

It is said that the facial muscles used on a daily basis are about 20% to 30%, and if metabolism is reduced by not using the muscles, it may cause swelling and sagging of fat. However, it is necessary to exercise caution because excessive exercise of the facial muscles may have the disadvantages of developing the masseter muscles and stretching the gills. The treatment with fat-dissolving injection destroys and dissolves excess fat on the face, which leads to improvement of sagging due to fat .

As a lipolytic injection around the face, in addition to the small face effect by injecting into the face line and cheeks, the effect of passing the nose muscles and shrinking the nose by injecting into the nose, improving the double chin by injecting below the chin You can expect an effect.

Sites that can be treated with lipolytic injections

Lipolysis injection can be performed on any area with subcutaneous fat.

Woman receiving a lipolysis injection

Facial fat

Eyelids, fat under eyes, cheeks, nose, face line, chin

Body fat

Neck, upper arm, chest (bust), abdomen (waist), back, hips, thighs, knees, calves, ankles

Suitable for fat-soluble injection

  • Resistant to major surgery such as liposuction
  • Improvement of fat that makes you feel the thickness of the eyelids
  • I want to clean my nose sting (dango nose)
  • Improvement of fat slack in the corners of the mouth and creases
  • Improved sagging of cheeks and face lines
  • Improvement of slack under the chin and double chin
  • Improving fat on your upper arm or bra
  • I want to reduce the bust volume
  • I want to adjust the waistline
  • Improvement of fat on the knees and calves
  • Improvement of fat in hips and thighs
  • Improvement of thick fat on the back
  • I want to lose weight naturally without being noticed by others

Differences in components of lipolysis injection and types of drugs

There are various types of drugs that are said to have a fat-dissolving effect, but they can be broadly divided into drugs containing phosphatidylcholine (PPC) and deoxycholic acid (DOC) and those containing plant extract ingredients. I can do it.

Although the same point that fat cells are destroyed and dissolved, the drug containing plant extract components is often used for facial treatments, and the difference is that inflammation and swelling are less than those containing PPC and DOC. there is.

Lipolysis injection

Main components of fat-dissolving injection

Phosphatidylcholine (PPC)

Phosphatidylcholine (PPC), which is often the main ingredient in fat-dissolving injections, is a type of amino acid extracted from soybean, lecithin. Originally used as a drug for the treatment of fatty liver and hyperlipidemia , it is said to function to enhance the metabolism of lipids and emulsify blood cholesterol to prevent cholesterol from adhering to blood vessel walls .

It has been said that lipolytic injections containing PPC as the main component require downtime of 1 to 2 weeks because inflammation and swelling are likely to occur. However, it is said that the improvement is now progressing, and inflammation and swelling are less than those of conventional drugs.

If you have a soybean allergy, please consult your doctor in advance.

Deoxycholic acid (DOC)

It is a medicinal ingredient that has been found to have a fat-dissolving effect by the US FDA (Food and Drug Administration) . Deoxycholic acid (DOC) is a type of bile acid originally contained in human bile, and is said to directly destroy the fat cell membrane by injecting it into the fat site.

According to recent research, it is said that there is a report that "the main one that solubilized fat cells was not PPC, but DOC that was added as a solubilizing agent for PPC."

Other fat-soluble drugs such as plant extracts

Each pharmaceutical company produces drugs that contain various fat-dissolving ingredients.

There are conventional drugs that do not contain PPC, DOC, etc. and are mainly composed of plant extract components that are said to have less inflammation, and drugs that combine deoxycholic acid with plant extract components.

Lipolytic injection to the face

Confirm the composition and characteristics of each drug for lipolysis injection

It is said that any drug can be injected into both the face and body, but there are many drugs that are not suitable for the face due to inflammation and strong swelling . Some drugs specialize in the fat-dissolving effect on the face, so be sure to treat with an appropriate drug under the diagnosis of your doctor.

Drug name component Feature
Revital cell foam Amino acids and vitamin components based on PPC Reduces downtime and helps to reduce swelling
Contour injection Ingredients derived from medical herbs Less swelling and almost no downtime
Regen slim Main component is PPC (not from soybean) DOC-free and relatively less swollen
Hyper repolisis Main components are PPC and DOC It has less inflammation and swelling than others, and is said to have a faster lipolytic effect.
Lipobean Main components are PPC and DOC While more effective than others, it has longer swelling and downtime. MFDS (Korean Food and Drug Administration) approved formulation
Sago Nimelt Ginkgo biloba extract, carnitine, etc. based on DOC Specialized in double chin treatment. Less swelling and inflammation
Fat x A high concentration of DOC as a main component, amino acids and carnitine derived from plant extracts Contains a drug that has a metabolism-promoting effect. There is downtime of several days to several weeks such as swelling and redness
Kaibera Main component is DOC Approved by the FDA (US Food and Drug Administration) as a double chin improving formulation in April 2015. While the lipolytic effect under the chin is strong, it has swelling and several days of downtime.
Caberin Carnitine and artichoke extract components are mixed with high concentration DOC as the main component. A drug with a high concentration of the active ingredient DOC of Kaibera. With less swelling and inflammation, not only double chin improvement but also slimming treatment of the whole body is possible.
BNLS Main components are plant extracts such as medical herbs and seaweed It is said to have excellent skin tightening and metabolic effects, has little inflammation and swelling, and is suitable for treating small faces.
BNLS Neo DOC combined with BNLS Improved drug for BNLS. There is almost no downtime such as inflammation or swelling, and it has the effect of lipolysis in a few days.
BNLS Ultimate Increased amount of deoxycholic acid from BNLS Neo, which has the function of causing inflammation and destruction of the cell membrane covering fat cells Improves the effect of lipolysis by including deoxycholic acid in the maximum concentration that does not cause side effects
Michelangelo Carnitine, caffeine, and alpha lipoic acid combined with PPC and DOC A compound with metabolic action is added to conventional drugs. It is said that pain and swelling are unlikely to occur.

Confirm the treatment interval, the market price and the number of fat-soluble injections by drug

Injection volume of lipolytic injection and interval between treatments

Woman on a successful diet

The lipolytic injection requires repeated treatment depending on the amount of fat and the site, but the fat cells at the site where the lipolytic injection is performed do not regenerate, and even if the treatment period is long, the fat-lytic effect in the next treatment may be improved. There is no problem .

Also, the treatment period, number of treatments, and injection amount depend on the treatment site, slimming target, and the drug for fat-dissolving injection, but in face treatment, the amount of fat is smaller than in the body, so it is completed with one treatment. It may be

Drugs containing PPC/DOC Drugs containing plant extracts
Feature It is said to cause inflammation and swelling although there are individual differences It is often used on the face and is said to have less inflammation and swelling than PPC and DOC
Injection volume of one treatment 2 to 10 injections (depending on the drug and site of treatment). Maximum injection volume is 5 for face and 50 for body
Treatment interval Can be injected 1 to 2 weeks apart Can be injected every other week


It is said that lipolytic injections containing plant extracts contain less inflammation and swelling than PPC and DOC, but there are individual differences in side effects. Follow the doctor's diagnosis regarding the treatment site and the number of treatments.

Price of Lipolysis Injection and Number of Injections

For lipolysis injection, one injection can be used to inject the drug into the site to be treated, divided into several pieces within the size of one postcard (10 cm x 15 cm).

Drugs containing PPC/DOC Drugs containing plant extracts
price From about 20,000 yen per bottle About 10,000 yen per bottle
Part Number Number of times Number Number of times
Eyelids (eye area) One Once~ 1~ Once~
nose 1~ 3 times~ 2 to 4 Once~
Cheeks (both) 1 to 2 3 times~ 2 to 4 Once~
Spiral line (both) 1 to 2 3 times~ 2 to 4 Once~
Face line 2 to 3 3 times~ 2 to 4 Once~
Double chin 1 to 3 3 times~ 3 to 5 Once~
neck 1~ 3 times~ 2 to 3 Once~
Upper arm (both) 5~ 3 times~ 20~ Once~
back 4~ 3 times~ 20~ Once~
abdomen 4~ 3 times~ 20~ Once~
Waist 4~ 3 times~ 10~ Once~
Hip (both) 8~ 3 times~ 20~ Once~
Thighs (both) 8~ 3 times~ 20~ Once~
Knees (both) 2~ 3 times~ 20~ Once~
Calf (both) 8~ 3 times~ 10~ Once~
Ankle (both) 2~ 3 times~ 20~ Once~

What you should know before surgery, such as the risk of lipolysis injection

Side effects and risks of lipolytic injection

It is said that the incidence of side effects and risks is low in lipolytic injections. However, it cannot be said that there is a possibility of causing serious side effects depending on your constitution. Before undergoing surgery, it is important to inform your doctor of your physical condition and allergies.

  • Swelling, warmth, redness, dull pain, itch (It is said that it will improve in about 1 week)
  • Rarely at the injection site (it is said that it will improve in a few months)
  • Internal bleeding at the injection site
  • Rare fever for 2 to 3 days
  • Allergic symptoms depending on constitution

Those who cannot receive fat-soluble injection

  • If you are pregnant or breastfeeding
  • Diabetes, heart disease, kidney disease, hypertension, hyperlipidemia, hyperthyroidism, etc.
  • Persons with soybean allergies are not eligible for PPC treatment.

Fat-soluble injections have no weight-loss effect

Although lipolytic injections are said to have the effect of reducing fat cells, they do not cause weight loss. Since fat has a lower density and a lower specific gravity than water, removing 1 liter of fat will not reduce it by 1 kg. Lipolysis injection is not for the purpose of weight loss, but for the purpose of adjusting the body line.

Repeated procedures are required for lipolytic injections

Since lipolysis injection is not a procedure in which changes occur immediately after one injection , repeated procedures may be necessary depending on the amount of fat and the site . The amount and number of injections vary from person to person, so please consult with your doctor and set a reasonable schedule.

To increase the effect of lipolysis injection

Woman exercising

After the treatment, it is said that by massaging the injection site, the lipolytic drug spreads to the fat layer and promotes the discharge of fat cells . However, if you have pain or swelling, it is important to refrain from massage and rest.

It is said that the fat cells at the site treated by the lipolytic injection do not regenerate, but on a regular basis, aim for a healthy body line by regular eating habits and moderate exercise.

Procedure of fat-soluble injection

The treatment time depends on the injection site of the lipolysis injection, but it will take about 5 to 20 minutes without anesthesia.

(1) Doctor diagnosis

The doctor will be informed of the treatment area, ideal line, and soybean allergy. If you have any concerns or concerns, try to resolve them during counseling.

(2) Anesthesia

It is said that there is relatively little pain because it is injected with an ultra-fine needle, but those who are not good at injection or who are vulnerable to pain are given epidermal anesthesia with anesthesia cream. Although there are individual differences, there may be a period of 1 to 2 weeks immediately after the procedure, with a hot sensation or muscle-like pain.

(3) Treatment

Drugs are injected into the areas where you are concerned about fat. If you have any pain or other abnormality at this time, tell the doctor immediately.

(4) After treatment

After confirming hemostasis at the injection site, the procedure will end. Also, depending on the medical institution, massage may be given to enhance the effect of the drug.

Beauty treatments that can be combined with lipolytic injections

  • Ella (masseter muscle) treatment with botulinum injection
  • Hyaluronic acid injection
  • Sag treatment with high frequency, HIFU, laser
  • Medical slimming drugs such as Xenical and Sanorex

Precautions after lipolysis injection

  • Avoid excessive exercise and drinking on the day of the procedure.
  • Please refrain from using the sauna, pool, and bath. Shower is not a problem.
  • For facial treatment, avoiding the injection site allows makeup to be applied immediately after the treatment.
  • Be sure to rehydrate with water to reduce inflammation.

Choosing an important doctor with a fat-soluble injection procedure

Woman enjoying summer fashion

Fat-dissolving injection is a simple slimming treatment that can be performed only by injection. However, delicate medical technology is required to inject the drug into the face with low fat mass.

If fat cells are destroyed more than necessary, such as around the eyes and cheeks, the firmness of the skin is lost and it often gives an old impression . In addition, it is said that fat cells once injected with a fat-dissolving drug and destroyed are not regenerated.

Therefore, it is important to select a doctor who is familiar with anatomy, can determine the amount of fat, and can predict the line after slimming . Let's aim for the ideal slim line with proper treatment by fat-soluble injection and regular lifestyle.