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Effect and progress / component characteristics of long-lasting injectable "Elance" by promoting ...




Satoshi Hashimoto
Dr. Satoshi Hashimoto

Certified by the Japanese Society of Cosmetic Surgeons Dermapen World Certified Dermapen 4 Technical Instructor suneKOS executive trainer in Japan Classys Certified Ultraformer 3 Instructor Endymed Certified Technical Instructor

Medical institution with Dr. Satoshi Hashimoto

Skin Finity Clinic Skin Finity Clinic
Contact: 0120-440-138

Elance Case Photo (Before After)
<Treatment fee in the above photo: 13,200 yen (tax included) Price for one Elance M>

"Elance", a skin injection agent that is injected subcutaneously using a syringe, has the characteristics that it has a long duration of about 1 to 3 years and that the ingredients are absorbed into the body and no foreign substances remain .

It is also used for treatments such as supplementing the volume of wrinkles and dents and contouring of the jaw, but it is noteworthy that it has the effect of promoting the production of collagen of its own, also called a collagen booster . By injecting with the aim of promoting collagen production, you can expect effects such as firmness and elasticity of the skin.

Other skin injections include hyaluronic acid and Lady Esse, but it is important to know what purpose you should choose Elance, as the appropriate injections will differ depending on the purpose of the procedure. In addition, it is possible to receive the treatment with more peace of mind by understanding in advance the period until the effect of the Elance treatment begins to appear and the risks and side effects.

Elance that promotes collagen production for a long period of time

Elance that has a long duration and promotes collagen production Developed in 2007, Elance is a cosmetological skin injection (Dermal Filler). A major feature is that it is used in the "collagen production promoting action ", which is also called collagen booster or bio-stimulator. In addition, by injecting pinpointly into areas of concern such as wrinkles and dents, you can expect the effect of supplementing the volume of the skin and leading to improvement.

It lasts up to 3 years , so you don't have to go to the hospital frequently. In addition, since the ingredients are absorbed into the body after injection, it is said that no foreign substances remain in the body, and there is a low risk of causing an allergic reaction when injected. Non-animal-derived, non-bacterial-derived, non-human-derived skin injection Since it is an agent, no prior patch test is required.

In addition to having obtained the European CE mark, Elance is said to be registered with the MFDS (formerly KFDA / Korea Food and Drug Administration) and the Australian TGA (Ministry of Insurance Drugs and Drug Administration), and is safe and effective. It is a recognized skin injection.

Ingredients of Elance that can improve wrinkles and improve skin quality

Elance is based on 70% CMC (carboxymethyl cellulose) and is composed of 30% PCL (polycaprolactone). Each is a non-toxic and non-allergic ingredient that has been approved for safety by the FDA (US Food and Drug Administration) and has a low risk of adverse effects on the human body. Antibodies are formed in the body even after repeated use. Since there is no such thing, it is said that the effect will not be diminished when injected even if multiple treatments are performed.

The two components that make up Elance have the following characteristics.

PCL, which is also a component of meltable sutures used in surgery

PCL (polycaprolactone) is a bioabsorbable soluble suture component used in surgical operations such as cardiac surgery and plastic surgery that does not require thread removal. After achieving the purpose, it is naturally decomposed and absorbed in the body by metabolism. Will be done. Elance contains PCL processed into fine particles with a diameter of 0.0025 mm to 0.005 mm.

PCL injected subcutaneously has the effect of promoting the production of new collagen, and improves wrinkles by regaining the firmness and elasticity of the skin that was lost with aging. In addition, since the speed of complete absorption into the body can be adjusted for each molecular structure of the PCL used, it is possible to select the duration according to the purpose of the treatment and the desired effect.

CMC that protects PCL and maintains viscosity

CMC (Carboxymethyl Cellulose) is a thickener manufactured from cellulose, water, and glycerin, which are components of plant fibers, and is a water- soluble substance widely used in pharmaceuticals, food additives, and cosmetics . CMC has the function of maintaining the proper elasticity and viscosity of Elance to maintain the shape of the gel, and also has the property of a protective colloid that uniformly disperses fine particles, so PCL particles are uniformly dispersed. It also has a role to make.

CMC, which is injected subcutaneously as a component of Elance, is absorbed into the body in about a month.

Three features of Elance

Elance promotes collagen production, which is responsible for skin elasticity

The firmness and elasticity of human skin is maintained by collagen, but the amount of collagen produced peaks in the 20s and decreases with age, so if nothing is done, the firmness and elasticity of the skin will gradually decrease. It will be lost .

Illustration of skin tissue

PCL contained in Elance has a function called "collagen booster" that promotes the production of new collagen around the injected subcutaneous area, so by injecting Elance into the dermis, the decreasing collagen is increased and the skin becomes firm. And elasticity is said to return .

In addition, PCL particles have the effect of causing slight inflammation around the injection site in the process of being absorbed into the body, and this inflammation stimulates the production of new collagen under the skin. , You can expect improvement of skin firmness and elasticity over a long period of time.

The return of elasticity and elasticity creates moisture on the skin , which leads to improvement of thin and delicate fine wrinkles under the eyes and fine wrinkles on the cheeks and outer corners of the eyes .

Elance has a long duration of effect

Collagen produced by the injection of Elance remains even after the injectant is absorbed into the body, so it can be expected to have the effect of increasing the firmness and elasticity of the skin for a long period of time and improving wrinkles. In addition, one of the features of Elance is that the speed of absorption into the body can be adjusted by changing the length of the molecule of PCL. there is.

product name Estimated duration
ELLANSE-S About 1 year
ELLANSE-M About 2 years
ELLANSE-L About 3 years

Elance has no limit on the number of treatments, so if it is no longer effective, you can re-inject it. The duration of the effect varies depending on the type of Elance injected, and there are individual differences. For example, when ELLANSE-L, which is expected to last for about 3 years, is injected, the treatment frequency is about once every 3 years.

The types of erances we handle vary depending on the medical institution, so please contact the medical institution in advance if you wish to use either type.

Elance components are absorbed after injection

After injection, PCL and CMC that make up Elance are decomposed into water and carbon dioxide over a certain period of time and absorbed into the body by hydrolysis, which is a phenomenon in which they are absorbed by reacting with water in the body. It is also called a fully absorbable injectable because no foreign matter remains in the body during the process of being decomposed and absorbed in the body.

For example, if you inject Elance, which has a duration of about 1 year, the volume will begin to decrease due to the bioabsorption of the ingredients about 1 year after the procedure.

Elance injection method and post-injection course

The treatment of Elance is basically an injection treatment by injection, and the part where wrinkles are worrisome or the part where you want to make the volume of the skin is marked with a surgical pen and injected, but the injection method is treatment It depends on the purpose of.

Inject thinly elance over a wide area

In the treatment aiming to improve the wrinkles under the eyes, the sagging cheeks, the back of the hands, etc. due to the decrease in the elasticity of the skin, the elasticity and elasticity of the skin can be improved by injecting erance thinly into a surface and applying the ingredients in a wide range. You can expect it.

When injecting Elance, you may use a cannula with a needle hole on the side, also known as a blunt needle. Since the cannula is flexible and can be bent, it is possible for the practitioner to adjust the direction of injection of Elance by rotating it under the skin, and the rounded tip makes it difficult to feel pain when injecting and causes internal bleeding. It is an injection needle that is said to have low risk.

In addition, some medical institutions use Dermapen, a pen-type medical device with 16 needles that are thinner than the hair, to allow a wide range of drugs with the same ingredients as Elance to penetrate the skin.

Inject Elance with pinpoint

By injecting erance pinpointly into the nasolabial fold, marionette line, temple dents, areas where the volume has decreased due to aging, and areas where you want to form contours, wrinkles and dents are improved by the action of supplementing the volume of the skin. You can also aim for contouring .

When injecting Elance pinpointly into the area of concern, it is common to use an injection needle of around 27G (diameter: 0.4mm) to inject into the deep part of the dermis, and contour formation. When Elance is injected for the purpose of, it is said that the effect can be felt immediately after the injection.

Estimated injection amount of Elance

When injecting Elance thinly over a wide area to improve the firmness and elasticity of the skin, the recommended injection amount is about 1cc per face. On the other hand, when injecting pinpointly to improve deep wrinkles such as nasolabial folds or to shape the contour, about 0.5cc to 2cc per site is a guide. Depending on the medical institution, the injection amount of Elance may be indicated by the number, but the capacity per one is 1cc.

The effect of Elance on improving the firmness and elasticity of the skin starts after 3 months.

The action of the collagen booster due to the injection of Elance will start to appear about 3 months after the injection .

Since Elance is absorbed into the body from the CMC after injection, when the swelling of the procedure subsides and the CMC is absorbed, it may feel that the volume is less than immediately after the injection. However, when the collagen production at the injected site is promoted by the action of PCL over 3 to 4 months, the skin's elasticity and firmness are gradually improved.

Progress Changes over time
Immediately after injection to about 3 days Swelling may occur due to the procedure
About a week Moisture may cause swelling in areas with thin skin, such as under the eyes
About 10 days to 2 weeks As CMC is absorbed into the body, it may feel like the volume is lower than immediately after injection.
About 3 months Collagen production is promoted by the action of PCL
After 3-4 months You will be able to feel the improvement of skin elasticity and firmness.

Those who are suitable for Elance

Those who want to regain the firmness and elasticity of the skin

By injecting it shallowly into the entire area of concern, you can expect to improve the firmness, texture, and elasticity of the entire skin. It can be expected to have the effect of improving problems such as "recently the tension has disappeared" and "worried about sagging as a whole".

Those who want to make wrinkles and dents less noticeable

Since the action of promoting collagen production of Elance can be expected to increase the firmness and elasticity of the skin, it is possible to supplement the volume by injecting it into wrinkles and dented areas.

  • Applicable parts: Nasolabial fold, marionette line, gorgo line, neck, forehead, temples, cheeks, mouth area, bear under the eyes, fine wrinkles at the corners of the eyes, back of the hand

Those who want to contour the nose and chin

Elance is an injectable agent that is excellent in improving and tightening the overall skin quality, lifting wrinkles and grooves by increasing elasticity and elasticity, and at the same time, it has the effect of supplementing the volume of the skin, so it forms the contour of the nose and chin. It is also possible to aim for.

  • Applicable parts: nose, chin, forehead, face line, cheeks

Differences between Elance and other injectables

Difference between erance and hyaluronic acid

Hyaluronic acid is an elastic component that originally exists in the body, so it is a viscoelastic substance that is compatible with the skin and has a low risk of allergies. Hyaluronic acid injection is suitable for purposes such as improving wrinkles and dents and forming contours that raise the nose, as it is an injection that excels at increasing skin height and volume.

Hyaluronic acid can be corrected by injecting a decomposing agent (hyaluronic acid) when the finish is different from what you want, but it does not promote the production of collagen in the skin like Elance . The main role of hyaluronic acid injection is to supplement the volume of the skin with the injection.

Difference between Elance and Lady Esse

Lady Esse is an injectable that tends to be used primarily for nasal and chin contouring because it is more viscous and elastic than erance and hyaluronic acid. The main component of Lady Esse is calcium hydroxyapatite, which is a component of bones and teeth, and since there is no decomposing agent, it cannot be modified like hyaluronic acid injection.

When hydroxyapatite is injected subcutaneously, it can be expected to promote collagen production in the same way as Elance. Since the duration of the effect is about one and a half to two years, it is a short- prone injectable agent compared to the long-lasting type of Elance, which has a duration of about three years.

Elance's procedure and precautions

(1) Medical examination and counseling

After receiving explanations such as the injection method of Elance and precautions for the treatment through medical treatment and counseling by the doctor, we will decide the site to inject and the desired duration. If you have any doubts or concerns about the procedure, please consult your doctor at this time.

(2) Face washing / cleansing

If the injection site of Elance is the face and you have applied makeup on the day of the procedure, cleanse and cleanse the face before performing the procedure.

(3) Marking / treatment

After marking the injection site with a surgical pen, inject Elance. Depending on the medical institution, it is possible to perform the procedure using an anesthetic tape or anesthetic cream if desired. The time required depends on the treatment site, but it takes about 10 to 30 minutes.

(4) Finish

You can go home immediately after completing the procedure. Makeup on the day of the treatment is also possible.

Notes on Elance

Pain when injecting Elance

There are individual differences in the degree of pain, but it is said that those who usually receive other injections such as hyaluronic acid injection without anesthesia do not feel pain with Elance injection. If you are worried about pain, you should choose a medical institution that can use anesthetic tape or anesthetic cream.

Those who cannot receive treatment by Elance

  • Pregnant and lactating
  • Those who have untreated infection and inflammation at the desired injection site
  • Those with blood coagulation disorders
  • Those with serious underlying diseases such as heart, kidneys and diabetes

Precautions after Elance treatment

  • Spend about a week after the procedure avoiding massage at the injection site and avoiding strong pressure.
  • Avoid long baths, strenuous exercise, and excessive drinking for about a week after the procedure.
  • Your doctor may tell you to avoid taking vitamins and aspirin after the procedure.

Elance downtime risks and side effects

After receiving an injection of Elance, inflammation and internal bleeding may cause mild swelling and redness for several days . Edema may occur in areas with thin skin, such as the eyelids and under the eyes, but it is said that it will subside in about a week.

Immediately after the injection of Elance, fine scars will be formed on the surface of the skin, but they will disappear within a few days if they can be covered with makeup.

Risks / side effects

Since Elance is a procedure in which a needle is inserted under the skin, there is a risk of internal bleeding if the capillaries are damaged. In addition, the fact that the erance does not spread in a plane may cause unevenness and lumps, and if the practitioner mistakenly injects the injectable into the blood vessel, the blood vessel may become clogged and skin necrosis may occur. If you notice any abnormalities, please consult your doctor immediately.

Also, since Elance does not have a decomposing agent like hyaluronic acid, even if the desired effect does not appear, you have to wait about 1 to 3 years until it is absorbed by the body.

Treatment that is good when used in combination with Elance

Hyaluronic acid injections, baby collagen injections, shopping lifts, etc. are good treatments to use together. Aiming to improve skin firmness, skin quality and volume by the action of collagen boost that Elance has, hyaluronic acid injection, baby collagen injection and shopping lift can be used in combination with deep wrinkles and other areas that you want to treat pinpointly. You can expect further skin-beautifying effect.

Elance rates

The amount of Elance varies depending on the duration, but the standard is 80,000 to 180,000 yen per bottle (1cc). Since the injection procedure of Elance is a free medical treatment, the fee setting differs depending on the medical institution.

What you need to know to receive Elance treatment with peace of mind

Elance is an injectable that cannot be redone because it has no degrading agent . If the finish is different from the image, such as overvolume after injection, or if a lump is formed, there is no choice but to wait until it is absorbed in the body. If you have a medical institution that has a large number of Elance treatments and publishes abundant case photos, or a medical institution that has a doctor who is familiar with skin anatomy, you can reduce the risk of failure that results in an unnatural finish.

For the purpose of contouring the nose and chin, there is also the option of first undergoing hyaluronic acid injection to see how the impression changes and then considering elance injection. You can choose the duration of your erance, but your medical institution may have a limited set of erances. If you are concerned about the duration, it is important to check in advance the duration of the erance handled by the medical institution receiving the treatment.

Elance of Skin Finity Clinic

Professor Satoshi Hashimoto, who supervised the article, taught me about Elance.

Are there any symptoms that make it easier to feel the effects of Elance?
Dr. Satoshi Hashimoto
By promoting the growth of collagen in the skin, the lost collagen is recovered, and it can be expected to improve the nasolabial fold, wrinkles on the forehead, pores, tightening, and overall skin quality.
Even after the treatment, the collagen booster will further increase collagen growth for several months, so it is characteristic that long-term effects can be obtained not only immediately after the treatment.
How painful is the procedure?
Dr. Satoshi Hashimoto
There is a tingling sensation when injecting, but some people receive the procedure without anesthesia. If you are worried about pain, you can use anesthesia to perform the procedure.
Please tell me about the disadvantages of Elance.
Dr. Satoshi Hashimoto
In addition to tightening and improving overall skin quality, Elance is sometimes used as a filler for the purpose of increasing volume as well as injecting hyaluronic acid.
Hyaluronic acid can be dissolved after injection, but the only disadvantage is that there is no solubilizer in Elance, so injection of Elance for the purpose of increasing volume should be carefully considered.
What is the treatment fee at the Skin Finity Clinic?
Dr. Satoshi Hashimoto
At our hospital, we perform Elance treatment with a menu called "Collagen Boost Injection". The type of formulation we handle is Elance M, which has a duration of about 2 years, and the price per bottle (1cc) is 132,000 yen (tax included).
Please tell me about downtime.
Dr. Satoshi Hashimoto
Swelling and redness may occur for several days. It's a good idea to have a downtime schedule for about a week, as it can swell for about a week in areas with thin skin, such as around the eyes. Immediately after the procedure, small scars will be formed on the surface of the skin, but they can be covered with makeup and will disappear within a few days.
Precautions ・ Please tell me about aftercare.
Dr. Satoshi Hashimoto
Please refrain from excessive drinking or long bathing for about a week after receiving the treatment. Promoting blood circulation can lead to prolonged downtime.
What kind of medical institution / doctor should I choose to receive Elance?
Dr. Satoshi Hashimoto
Elance is a treatment whose effect varies depending on the injection technique of the practitioner, and especially the method of injecting shallow elance evenly and widely requires delicate and high injection technique. If you have a doctor in the past who was satisfied with the result of an injection procedure such as hyaluronic acid injection, it is a good idea to leave the procedure to that doctor.
Please give a message to those who are wondering whether to receive Elance.
Dr. Satoshi Hashimoto
The most attractive feature of the Elance preparation is its role as a "collagen booster" because it has an excellent collagen-enhancing effect necessary for improving one's own skin quality. It is a treatment that can pursue a more natural finish when there is resistance to the swelling feeling like hyaluronic acid.
Dr. Satoshi Hashimoto
However, on the other hand, when using it as a collagen booster, it is treated by a completely different injection method from hyaluronic acid injection, so it is important to ask a doctor you trust.
Thank you Professor Hashimoto!

Introduction of supervising doctor

Dr. Satoshi Hashimoto, the director of the Skin Finity Clinic, boasts an overwhelming number of cases and uses in Japan for the treatment of Elance, which requires high injection technology. He is familiar with the characteristics of Elance and the action of biostimulators that cause collagen hyperplasia, and gives many lectures such as study sessions and seminars on injection techniques for doctors. He also serves as an instructor for multiple treatments such as Dermapen 4, and energetically promotes the correct treatment method.

Medical institution with Dr. Satoshi Hashimoto

Skin Finity Clinic Skin Finity Clinic
Contact: 0120-440-138

Elance is an unapproved drug from the Ministry of Health, Labor and Welfare.
Drug acquisition route: The acquisition route is individual import from the manufacturer by the doctor of each medical institution.
Drugs to be aware of when importing personally (Ministry of Health, Labor and Welfare page)

Whether or not it is approved in Japan: There is no drug that has the same ingredients and actions as Elance and has been approved in Japan.

Information on safety in other countries: The side effects reported to the US FDA (US Food and Drug Administration) for general dermal fillers are as follows.
Common side effects: bruising, inflammation, swelling, pain, itching, rash that resolves within 2 weeks Very rare side effects: granulomas, infections, allergic reactions, necrosis, omissions, infusion transfer , Visual abnormalities, stroke, etc. [*]

[*] Dermal Fillers (Soft Tissue Fillers): FDA