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Effects and risks of MiraDry used to treat armpit odor and hyperhidrosis



Axillary odor, also known as armpit, is a disease in which the armpits give off a peculiar foul odor due to sweat . Hyperhidrosis is a disease in which you sweat more than you need to regulate your body temperature .

To improve armpits and hyperhidrosis, use a scalpel to physically remove the sweat glands that drain sweat, use a machine without a scalpel to destroy, or incinerate and coagulate the sweat glands. There is a method and a method to temporarily suppress sweating by injecting a drug.

MiraDry is one of the machines that cauterizes and coagulates sweat glands, and can irradiate microwaves that generate heat in response to water . By irradiating the treatment site with microwaves, it can be expected to improve armpits and hyperhidrosis.

By checking downtime, risks, precautions, etc. before performing MiraDry treatment, you can receive treatment with peace of mind.

Eccrine and apocrine glands that drain sweat

The human body works to regulate sweat and regulate body temperature in order to prevent heat stroke that causes various symptoms such as convulsions and headaches due to the rise in body temperature due to exercise and high temperature environment.

In Europe and the United States, sweat discharge due to exercise and high temperature environment is often recognized as a physiological phenomenon, so it is said that few people are disgusted by the "smell" and "yellowing of clothes / sweat stains" caused by sweat. ..

However, in Asia, it is said that many people are disgusted by the odor caused by sweat, yellowing of clothes, and sweat stains due to differences in odor caused by sweat and cultural differences from those in Europe and the United States.

The smell of sweat, yellowing of clothes, and sweat stains are caused by sweat glands called eccrine glands and apocrine glands that drain sweat .

Therefore, many Asians use machines to remove sweat glands that drain sweat, destroy or incinerate or coagulate sweat glands, or inject drugs to improve the odor, yellowing, and sweat stains caused by sweat. It is said that there are many people who perform treatments to temporarily stop the discharge of sweat.

Causes of hyperhidrosis and sites of onset

Hyperhidrosis is a condition in which more sweat than usual is discharged due to exercise, high temperature environment, autonomic imbalance, etc., which interferes with daily life .

Hyperhidrosis can range from relatively mild to severe. The relatively mild symptom is to excrete more sweat than usual due to exercise, high temperature environment, autonomic imbalance, etc., and in the severe case, a large amount from the side regardless of the presence or absence of exercise, high temperature environment, autonomic imbalance, etc. Is to drain the sweat .

For severe hyperhidrosis, there is primary axillary hyperhidrosis.

The cause of hyperhidrosis is a sweat gland called the eccrine gland that drains sweat . Eccrine glands are sweat glands that are particularly developed in the human body. It is a sweat gland that has an outlet (opening) that discharges sweat from the epidermis, is distributed almost throughout the body, and discharges a large amount of sweat.

In addition, 99% of the sweat excreted from the eccrine glands is made up of water and the remaining 1% is made up of salt. The sweat discharged from the sweat glands mainly has the role of controlling body temperature and moisturizing the skin.

Sweat from the eccrine glands is said to be colorless and odorless, but if the sweat contains garlic or spices ingested in the diet, it is said to cause a foul odor.

There are two types of sweat glands, the eccrine gland and the apocrine gland. The eccrine gland, which is particularly developed in humans, has a high sweat-secreting ability and is distributed almost on the entire body surface.

Source: Sweat and Health

Areas where hyperhidrosis is likely to occur

  • head
  • hand
  • Armpit
  • Foot soles, etc.

Causes of body odor and areas of onset

Apocrine glands with openings near the hair roots are sweat glands that are distributed in limited areas such as the armpits and vulva and emit less sweat. The sweat that has just been excreted from the apocrine sweat glands is odorless, but the color of the sweat is milky white because it contains "neutral fat," "fatty acids," "protein," "ammonia," and "iron."

Neutral fats, fatty acids, proteins, ammonia, and iron contained in sweat are decomposed by bacteria attached to the surface of the skin to produce small fatty acids, which causes "armpits" .

It is said that people with more developed apocrine glands are more likely to become "armpits". It is said that the development of apocrine glands is related not only to genetic factors and sex hormones, but also to mental factors such as armpit hair volume, stress and tension, and sweating due to exercise.

Body odor also has relatively mild to severe symptoms. Mild symptoms are said to be mild when you put gauze on your side and bring the gauze close to your nose and it smells . It is considered a serious symptom that the odor can be noticed just by holding the gauze in the hand .

Areas where body odor is likely to occur

  • Armpit
  • Ear canal
  • Eyelid edge
  • nose
  • Areola
  • belly button
  • anus
  • Vulva

The effects and characteristics of MiraDry, which can be expected to improve armpits and hyperhidrosis

MiraDry can be expected to improve armpits and hyperhidrosis by using microwaves, which are a type of electromagnetic waves.

Electromagnetic waves have "wavelength" and "frequency". The length of the wave of one waveform that repeats the peaks and valleys of electromagnetic waves is called the wavelength, and the wave (vibration) of the waveform that repeats the peaks and valleys is called the frequency.

The frequency is represented by the frequency, which is the number of times a wave with a waveform that repeats peaks and valleys appears per second, and the frequency is expressed in units of 〇Hz (hertz).

Electromagnetic waves are classified into gamma rays, X-rays, ultraviolet rays, visible rays, infrared rays, microwaves, and high frequencies according to the difference in wavelength and frequency. Electromagnetic waves with a wavelength of 1 m to 1 mm at a frequency of 300 MHz to 300 GHz are regarded as microwaves. I am .

Electromagnetic waves with frequencies of 300 MHz to 300 GHz (wavelength 1 m to 1 mm) are called microwaves (the region of 1 cm or less is millimeter waves).

Source: Basics and applications of microwave heating of metals

The characteristic of this microwave is that it is absorbed by moisture and generates heat . For example, microwave ovens, which are often used at home, also use microwaves. The principle of heating foods such as vegetables and meat in a microwave oven is that the water contained in the food absorbs microwaves and the water molecules vibrate and rotate to generate heat, which can heat the food.

MiraDry is a machine that uses the characteristics of microwaves to treat armpit and armpit hyperhidrosis. The sweat glands, which cause armpits and hyperhidrosis, retain a lot of water.

Therefore, when irradiated with microwaves, it is absorbed by the water possessed by the sweat glands and generates heat . By cauterizing and coagulating the sweat glands with the generated heat, it leads to improvement of hyperhidrosis and armpits .

MiraDry uses frequencies with a low risk of burns

It is said that the frequency at which microwaves react most with water and are easily absorbed is around 18 GHz. However, it is said that if it reacts too much with moisture, the amount of heat generated will increase and the risk of burns will increase.

In clinical trials using tissues on the epidermal side, it has been found that the microwave frequency element with the lowest risk of causing burns is 5.8 GHz . MiraDry uses this 5.8GHz frequency microwave and is said to have a low risk of burns.

Analysis showed that the 5.8 GHz frequency had a lower absorption rate for epidermal tissue than the other frequencies and had the lowest risk of causing burns among the three frequencies.

Source : MiraDry Deliberation Report Page 10

MiraDry can adjust the irradiation time according to the side symptoms

MiraDry can adjust the microwave irradiation time from mild armpit and hyperhidrosis symptoms to severe armpit and hyperhidrosis symptoms .

There are five levels of microwave irradiation time: 2.40 seconds, 2.55 seconds, 2.70 seconds, 2.85 seconds, and 3 seconds. Depending on the medical institution, levels 1, 2, 3, 4, and 5 are listed in ascending order of irradiation time.

By adjusting the irradiation time according to whether the patient has armpit or hyperhidrosis and the severity of the symptom, it is possible to improve the armpit and hyperhidrosis of patients in various conditions.

MiraDry can be expected to be highly effective and long-lasting with a single treatment

MiraDry does not treat the sweat glands one by one, but can cauterize and coagulate the area where the sweat glands exist by irradiating them with microwaves . Therefore, it is said that a single treatment can be expected to be highly effective in improving armpits and hyperhidrosis.

In addition, since cauterized and coagulated sweat glands are not regenerated, it is said that long-term sustained effects can be expected to improve armpits and hyperhidrosis .

MiraDry is a medical device approved by the Ministry of Health, Labor and Welfare

MiraDry is a machine developed by Miramar Labs in the United States (USA) for the treatment of armpit and hyperhidrosis. The US FDA (Food and Drug Administration), which is the Ministry of Health, Labor and Welfare of Japan, shows the effects and safety of "treatment of primary axillary hyperhidrosis", "adaptation for axillary hair loss", and "reduction of axillary odor during treatment of primary axillary hyperhidrosis". Sex is recognized.

In Japan, in June 2018, the Ministry of Health, Labor and Welfare approved the efficacy and safety of "treatment of primary axillary hyperhidrosis". (Medical device approval number: 23000BZX00161000 )

Approval / permission of MiraDry in major foreign countries, or purpose of use

Country name Permit date
(Permission number)
Intended use
USA October 25, 2013
Treatment of primary axillary hyperhidrosis
USA June 19, 2015
Added indications for axillary hair loss
USA October 31, 2016
Added axillary odor reduction effect when treating primary axillary hyperhidrosis
Taiwan March 19, 2014 Treatment of primary axillary hyperhidrosis Axillary hair loss
UAE September 28, 2015 Treatment of primary axillary hyperhidrosis
China May 20, 2015 Treatment of axillary hyperhidrosis
Korea July 11, 2012 Treatment of hyperhidrosis
Canada October 20, 2012 Between treatments for primary axillary hyperhidrosis

Those who are suitable for MiraDry treatment and those who are not

Those who are suitable for MiraDry treatment

  • Those who have a lot of side sweat and are always moist
  • Those who get yellowed clothes due to sweat stains
  • Those who are worried that the smell of the side is not noticed by the people around them
  • Armpit sweat ・ Those who are looking for a way to maintain the effect of odor
  • Those who want to receive treatment with peace of mind using a machine approved by the Ministry of Health, Labor and Welfare

Those who cannot and may not be able to perform MiraDry

Those who cannot perform MiraDry

  • Those who have undergone extensive lymph node dissection
  • Those who have undergone breast reconstruction by axillary incision
  • Those who have undergone axillary surgery
  • Pregnant or lactating

Those who may not be able to perform MiraDry

Those who fall under the following may not be able to receive the treatment at the discretion of the doctor.

  • Those with less subcutaneous fat on the side
  • Those who are taking drugs that reduce immunity or interfere with postoperative healing
  • Obese
  • Those who have extensive wrinkles on the skin and have difficulty transferring the template
  • Those with a wide range of skin disorders such as eczema or psoriasis

Pain during MiraDry treatment and recommended number and frequency of treatments

Pain during MiraDry treatment

For MiraDry, apply anesthesia cream before the procedure, or give laughing anesthesia and then give local anesthesia to the side. Therefore, it is said that there is almost no pain during local anesthesia or during the procedure .

However, if the anesthesia begins to run out after the procedure, it may cause tingling pain and skin tension .

The tingling pain and tightness of the skin can be relieved to some extent with a pain reliever, so please consult with your doctor so that you can prescribe a pain reliever at the clinic where you received the treatment.

Number and frequency of treatments recommended by MiraDry

It is said that many people feel the effect of MiraDry with one treatment.

However, if you do not feel the effect of one treatment, a second treatment is recommended .

When performing the second treatment, it is recommended to wait about 3 months after the first treatment .

MiraDry downtime and rare risks / side effects and precautions

MiraDry downtime

About 2 weeks after MiraDry treatment, redness and subcutaneous induration (usually soft tissue becomes hard due to inflammation etc.) may occur, but it is said that it gradually subsides.

In addition, swelling around the sides, suction marks, and discomfort after treatment are said to subside in about a week .

Risks and side effects of MiraDry

Risks and side effects of improper use of MiraDry by doctors

  • Damage to the radial nerve with weakness of the triceps brachii
  • 2nd degree burn
  • 3rd degree burn

* The severity of burns is roughly divided into three levels: 1, 2, and 3.

☆ Once the skin becomes red and tingling , it is said that it will settle down in a few days due to burns only on the epidermis.

☆ The feature is that not only the epidermis but also the dermis can be burned and blisters twice. In addition, if the burn is relatively mild (superficial), the pain is strong, and if it is severe (deep), the pain is weak . It depends on whether the burn is mild or severe, but it is said that it will subside in about 1 to 4 weeks .

☆ When it reaches 3 degrees, not only the epidermis and dermis but also the subcutaneous tissue is burned and nerves and blood vessels are damaged, so it is characteristic that no pain is felt . It is also characterized by the fact that the skin loses blood and looks white or black. Surgery is required for three burns, often requiring a treatment period of one month or longer .

Rare risks and side effects of receiving MiraDry

  • 1st burn
  • 2nd degree burn
  • Abscess
  • A feeling of strangeness from the hand to the elbow
  • Chronic cyst
  • Infection
  • Necrosis
  • Thrombophlebitis
  • Ulcer
  • Weakness of arms and fingers
  • Compensatory sweating
  • Dermatitis
  • Axillary nodules or nodules
  • Uncomfortable feeling of swelling or bumpy skin on the side
  • Swelling (swelling) of the upper arm or chest
  • Internal bleeding or bleeding at the injection site due to local anesthesia
  • Transient numbness in the armpit due to anesthesia
  • Posture-induced irritation or discomfort
  • Numbness, tingling, irritability, other internal bleeding, and tight skin after anesthesia is cut off
  • Numbness, tingling sensation, pain (depression), tenderness (attriety), irritation, lymphedema (swelling), edema, blisters, rash, heat sensation after treatment
  • complications

Notes on MiraDry

Precautions before MiraDry treatment

  • The template for MiraDry used when marking the sides uses soy ink. Therefore, if you are allergic to soybeans, please consult your doctor in advance.
  • Do not cool your armpits before the MiraDry procedure
  • Shave your armpits before the MiraDry procedure
  • Remove metal accessories such as piercings and watches before the MiraDry procedure
  • The heat destroys the hair follicles adjacent to the eccrine sweat glands, which can lead to hair loss on the sides.

Precautions after MiraDry treatment

  • Makeup is possible immediately after the treatment, but please wash your hair and shower from the next day.
  • It is usually said that you can act from the next day, but there are individual differences in side pain and swelling. It is said that those who are uneasy should not schedule work the next day.
  • After the treatment, please perform icing to cool the side for 2 to 3 days.
  • Please refrain from bathing, shaving your armpits, using antiperspirants, and strenuous exercise for 4 days after the procedure.
  • When performing the second treatment, wait about 3 months after confirming the treatment effect.
  • Even if there is an interval of about 3 months, do not perform more than necessary treatments on the same site up to 3 times.

Advantages and disadvantages of MiraDry

Benefits of MiraDry

The effect can be expected immediately after the treatment

Since MiraDry can cauterize and coagulate sweat glands, it is said that the effect can be felt immediately after the treatment .

Disadvantages of MiraDry

The remaining sweat glands may become active and feel like they have recurred.

MiraDry can be expected to be highly effective with a single treatment, but not all sweat glands are cauterized and coagulated .

Therefore, it is said that MiraDry may activate the sweat glands that remain without cauterization and coagulation , causing the sweat to increase and the odor to recur .

May cause compensatory sweating

Cauterizing and coagulating the sweat glands under the armpits with MiraDry may increase the amount of sweat in areas where sweat glands are present, such as the vulva and areola, or may cause compensatory sweating with increased odor .

Differences between treatments other than MiraDry, which can be expected to be effective against armpits and hyperhidrosis, and MiraDry

Difference between MiraDry and View Hot

View hot is a machine that can generate electromagnetic waves called RF (radio waves) .

36 needles are attached to the tip of the handpiece used in View Hot, and the size of the needle is 30G (gauge). G is a unit that expresses the thickness of the needle, and the larger the number, the thinner the needle.

Usually, the needles used for intravenous drip and blood collection are said to be 17G to 23G, so it can be said that the needles of View Hot are extremely fine. By piercing the treatment site with this thin needle and irradiating it with radio waves, the sweat glands that cause armpits and hyperhidrosis are destroyed. View Hot is a procedure that destroys the sweat glands by piercing the needle, leaving traces of needle holes in the punctured area .

However, it is said that the needle marks will settle down in a few weeks to a month. </ Span> In addition, View Hot can be applied to any part of the body. </ Span>

MiraDry, on the other hand, is a method of cauterizing and coagulating sweat glands with the heat generated by irradiating microwaves. After the treatment, there may be redness, swelling around the treatment site, and discomfort, but it is said that it will subside in about 1 to 2 weeks.

In addition, MiraDry is recommended to be treated only on the side. Therefore, if the symptom you want to improve is your hands or feet, it is said that View Hot is suitable. In addition, it is said that MiraDry is suitable for those who are not good at needles with only armpit treatment or who want treatment with short downtime.

Difference between MiraDry and Botulinum (Botox) injection

Botulinum injection is widely known as the so-called "Botox injection", but Botox is the product name "Botox Vista" registered by Allergan, Inc., not the treatment name.

The drug used for botulinum injection is based on a toxin called botulinum toxin extracted from Clostridium botulinum. Botulinum toxin has the effect of suppressing the action of neurotransmitters that instruct the eccrine and apocrine glands to sweat from the brain.

Botulinum toxin can suppress the action of neurotransmitters and temporarily suppress sweating, but the effect is about 4 to 9 months, so repeated treatments are required . In addition, botulinum injection can be applied not only to the sides but also to the forehead, nose, palms, and soles of the feet .

On the other hand, MiraDry can suppress sweating by cauterizing and coagulating the eccrine glands and apocrine glands, so it can be expected to have a long-lasting effect after the treatment.

For those who want a long-term lasting effect, MiraDry is suitable. However, since the treatment area is only on the side, botulinum injection is suitable when you want to suppress sweating on the forehead, nose, palms, and soles of the feet, or when you want to temporarily suppress sweating without destroying the sweat glands.

Difference between MiraDry and the shearing method

The shearing method is a method of suppressing sweating by using a scalpel to make an incision in the area of concern for armpits and hyperhidrosis, and physically removing the eccrine and apocrine glands.

Once removed, the eccrine and apocrine glands are not regenerated and are less likely to recur. However, it is said that it takes about 3 to 6 months for the scars on the surgical site to become inconspicuous due to surgery to open the skin.

In addition, it is necessary to put a gauze mass aside (postoperative fixation) to prevent complications due to bacterial infection and to prevent the incision scars from adhering and becoming keloid . Therefore, it is not possible to completely close the armpits, which requires restrictions in daily life .

MiraDry, on the other hand, does not make an incision in the skin, so it is said to leave no scars. The downtime is as short as 1 to 2 weeks, and there is no need for postoperative fixation after the procedure, so there is no problem in daily life.

MiraDry treatment flow and price quotes

Flow of MiraDry treatment

(1) Counseling / medical examination

Tell us the symptoms you want to improve and check the condition of your skin to see if the procedure can be performed. In addition, you will be informed of the risks / side effects, downtime and precautions before receiving the treatment. In addition, if you have any questions or concerns, please consult with us at the time of medical examination and counseling, and then receive the treatment after you are satisfied.

(2) Shaving

Some medical institutions will instruct you to shave before your visit. However, if you have forgotten to shave or have leftovers, shave before the procedure.

(3) Marking using template

Use 12 different sizes of templates to determine the size that fits your side. After deciding the size, use a magic pen etc. to mark according to the template. After marking, attach a transfer sheet exclusively for MiraDry, which describes in detail the part to be anesthetized locally and the part to be irradiated with microwaves, according to the marked part. In addition, moisten the transfer sheet with cotton containing 70% or more alcohol and transfer it to the side.

(4) Anesthesia

Apply anesthesia cream to the side or perform laughing anesthesia, and then perform local anesthesia. Depending on the anesthesia, it may take 20 to 30 minutes for the effect to appear.

(5) Apply lubricant and irradiate MiraDry

After applying a thin layer of water-soluble lubricant to the entire armpit, irradiate MiraDry while adjusting the irradiation time according to the symptom you want to improve.

(6) Remove lubricant and template ink for icing

After the treatment, remove the lubricant applied to the side and the ink of the template, and then apply an ice pack to perform icing. Estimated treatment time is about 60 to 75 minutes on both sides. After the treatment, the doctor will explain the precautions after the treatment, so you can go home within the day.

MiraDry price quote

MiraDry costs about 300,000-400,000 yen per treatment .

If you do not feel the effect of one treatment, you can receive the second treatment. The second treatment tends to be less expensive than the first .

In addition, MiraDry is not covered by insurance, so you will be responsible for all the treatment fees. Depending on the medical institution, you can choose a flat-rate payment method with a low interest rate that can be used only during treatment called medical installment payment (loan).

How to choose a medical institution to receive MiraDry treatment

MiraDry is a machine that can be expected to improve armpits and hyperhidrosis by adjusting the irradiation time according to the symptom you want to improve.

Therefore, the doctor needs to check the condition of the armpit and adjust the irradiation time. A doctor who is familiar with anatomy is relieved to diagnose the condition of the treatment site .

In addition, MiraDry, the developer of MiraDry, has an officially certified medical program for MiraDry procedures. If you complete the official certification program and have a doctor who is qualified as a certified doctor, you will feel more secure and you will get the expected effect .